Grease and flour a loaf pan, and preheat the oven to 350 F.
Whisk the dry ingredients together in a medium-sized bowl (flour, baking soda, baking powder, pumpkin pie spice, and salt).
Using a hand-held or stand mixer, cream the butter and sugar together at medium speed until soft and fluffy.
Add the eggs and pumpkin puree and beat until combined (don’t worry if it doesn’t look smooth).
Add the dry ingredients to the butter and pumpkin mixture, and beat on slow speed just until combined.
Spoon the batter into the prepared pan and bake for 60-70 minutes or until a toothpick inserted in the middle comes out clean. Let cool in the pan for about 10 minutes, then unmold and transfer to a cooling rack to cool completely.